- Industria: Government; Health care
- Number of terms: 6957
- Number of blossaries: 0
- Company Profile:
The National Cancer Institute (NCI) is part of the National Institutes of Health (NIH), which is one of 11 agencies that compose the Department of Health and Human Services (HHS). The NCI, established under the National Cancer Institute Act of 1937, is the Federal Government's principal agency for ...
一种含有磷放射性同位素的放射性核素放射性物质。由磷P32释放，β粒子直接破坏细胞DNA，通过电离胞内水来产生几种不同类型的细胞毒性自由基和超氧化物，间接损害细胞内的生物分子，从而导致肿瘤细胞死亡。
Industry:Pharmaceutical
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Industry:Pharmaceutical
放射性碘同位素，一种卤族非金属元素。碘125的半衰期为60天，可以在自然界找到，也可以人工生产。碘可以用于疾病治疗和诊断，特别是甲状腺疾病。
Industry:Pharmaceutical
Potansiyel antianjiyogenez ve antineoplastik aktiviteleri olan bir pirazolobenzodiazepin küçük molekülü. Mitoz-anjiyogenez inhibitörü (MAI) R1530, vasküler endotelyal büyüme faktörü reseptörü (VEGFR) -1, -2, -3, trombosit kaynaklı büyüme faktörü reseptörü (PDGFR) beta ‚FMS-benzeri gibi anjiyogenezde rol oynayan çoklu reseptör tirozin kinazları inhibe eder. tirozin kinaz (Flt) -3 ve fibroblast büyüme faktörü reseptörü (FGFR) -1, -2. Ek olarak, bu ajanlar, mitotik arrest başlatarak ve apoptozu indükleyerek anti-proliferatif aktivite sergiler.
Industry:Pharmaceutical
Ein Purinderivat mit antineoplastischen und antiangiogenen Eigenschaften. 6-Methylmercaptopurin-Ribosid (6-MMPR) inhibiert Amidophosphoribosyltransferase, den ersten festgelegten Schritt in der De-novo-Purinsynthese, und inhibiert die Fibroblastenwachstumsfaktor-2 (FGF2)-induzierte Zellproliferation.
Industry:Pharmaceutical
Una saponina natural purificada aislada del arbol Quillon, Quillaja saponaria Molina, con actividad inmunoadyuvante potencial. Cuando se lo coadministra con los péptidos de vacuna, OPT-821 puede incrementar las respuestas de los anticuerpos y de los linfocitos T citotoxicos contra el (los) antígeno(s) destinatario(s).
Industry:Pharmaceutical
Un inhibidor de la proteasa que se utiliza para combatir el virus de la inmunodeficiencia humana (VIH). El lopinavir inhibe de manera competitiva la proteasa del VIH-1, una enzima que interviene en la separacin de los polipptidos precursores Gag, Gag-Pol y Nef en sus protenas maduras, incluidas la proteasa, la transcriptasainversa y la integrasa. La inhibicin de la proteasa del VIH-1 impide la separacin de la poliprotena viral precursora y tiene como consecuencia la emisin de viriones inmaduros y no infecciosos.
Industry:Pharmaceutical
Spezieller Protein-Kinase-Inhibitor fr Raf- und Mitogen-aktivierte Protein-Kinase (MAPKs) mit potentieller anti-neoplastischer Wirkung. Der duale Raf/MEK-Kinase-Inhibitor RO5126766 hemmt speziell die Kinase-Aktivitten von Raf and MEK, was zur Hemmung von Zielgen-Transkription fhrt, welche die maligne Transformation von Zellen frdert.
Industry:Pharmaceutical
Saponin purificat, natural, extras din arborele Quillaja saponaria Molina, cu poten?ial activitate imunoadjuvant. Cnd este co-administrat cu peptidele vaccinurilor, QS21 poate cre?te rspunsul total al anticorpilor vaccin-specifici antitumorali ?i rspunsurile celulelor T citotoxice.
Industry:Pharmaceutical
从植物芦荟（百合科）的实质组织制备叶浆。 芦荟凝胶含有碳水化合物聚合物，如葡甘露聚糖或果胶酸，以及各种维生素和必需氨基酸，以及其他有机和无机化合物。 该药剂被用作处理皮内或皮外晒伤，皮肤问题，昆叮虫咬，溃疡，关节炎，便秘以及免疫系统增强剂。
Industry:Pharmaceutical
